The Framingham Heart Study is a project of Boston University & the National Heart, Lung, & Blood Institute.
The Framingham Heart Study is a project of Boston University & the National Heart, Lung, & Blood Institute.

Framingham Heart Study Bibliography – 2020

January

Agami S, Zucker DM, Spiegelman D. Estimation in the Cox survival regression model with covariate measurement error and a changepoint. Biom J. 2020. Epub 2020/02/01. doi: 10.1002/bimj.201800085. (PubMed ID Number: 32003495).

Agarwal R, Song RJ, Vasan RS, Xanthakis V. Left Ventricular Mass and Incident Chronic Kidney Disease. Hypertension. 2020;75(3):702-6. Epub 2020/01/14. doi: 10.1161/hypertensionaha.119.14258. (PubMed ID Number: 31928112).

Granot-Hershkovitz E, Wu P, Karasik D, Peter I, Peloso GM, Levy D, Vasan RS, Adrienne Cupples L, Liu CT, Meigs JB, Siscovick DS, Dupuis J, Friedlander Y, Hochner H. Searching for parent-of-origin effects on cardiometabolic traits in imprinted genomic regions. Eur J Hum Genet. 2020;28(5):646-55. Epub 2020/01/04. doi: 10.1038/s41431-019-0568-1. (PubMed ID Number: 31896779).

Ji H, Kim A, Ebinger JE, Niiranen TJ, Claggett BL, Bairey Merz CN, Cheng S. Sex Differences in Blood Pressure Trajectories Over the Life Course. JAMA Cardiol. 2020;5(3):19-26. Epub 2020/01/16. doi: 10.1001/jamacardio.2019.5306. (PubMed ID Number: 31940010; PMCID: PMC6990675).

Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, Taliun D, Cade BE, Wang H, Daya M, Ziniti J, Datta S, Celedón JC, Soto-Quiros ME, Avila L, Weiss ST, Barnes K, Redline SS, Vasan RS, Johnson AD, Mathias RA, Hernandez R, Wilson JG, Nickerson DA, Abecasis G, Browning SR, Zöllner S, O’Connell JR, Mitchell BD, O’Connor TD. De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population. Proc Natl Acad Sci U S A. 2020;117(5):2560-9. Epub 2020/01/23. doi: 10.1073/pnas.1902766117. (PubMed ID Number: 31964835; PMCID: PMC7007577).

Lee CM, Woodward M, Batty GD, Beiser AS, Bell S, Berr C, Bjertness E, Chalmers J, Clarke R, Dartigues JF, Davis-Plourde K, Debette S, Di Angelantonio E, Feart C, Frikke-Schmidt R, Gregson J, Haan MN, Hassing LB, Hayden KM, Hoevenaar-Blom MP, Kaprio J, Kivimaki M, Lappas G, Larson EB, LeBlanc ES, Lee A, Lui LY, Moll van Charante EP, Ninomiya T, Nordestgaard LT, Ohara T, Ohkuma T, Palviainen T, Peres K, Peters R, Qizilbash N, Richard E, Rosengren A, Seshadri S, Shipley M, Singh-Manoux A, Strand BH, van Gool WA, Vuoksimaa E, Yaffe K, Huxley RR. Association of anthropometry and weight change with risk of dementia and its major subtypes: A meta-analysis consisting 2.8 million adults with 57 294 cases of dementia. Obes Rev. 2020;21(4):e12989. Epub 2020/01/04. doi: 10.1111/obr.12989. (PubMed ID Number: 31898862; PMCID: PMC7079047).

McGrath ER, Himali JJ, Xanthakis V, Duncan MS, Schaffer JE, Ory DS, Peterson LR, DeCarli C, Pase MP, Satizabal CL, Vasan RS, Beiser AS, Seshadri S. Circulating ceramide ratios and risk of vascular brain aging and dementia. Ann Clin Transl Neurol. 2020;7(2):160-8. Epub 2020/01/18. doi: 10.1002/acn3.50973. (PubMed ID Number: 31950603; PMCID: PMC7034495).

Shah S, Henry A, Roselli C, Lin H, Sveinbjörnsson G, Fatemifar G, Hedman Å K, Wilk JB, Morley MP, Chaffin MD, Helgadottir A, Verweij N, Dehghan A, Almgren P, Andersson C, Aragam KG, Ärnlöv J, Backman JD, Biggs ML, Bloom HL, Brandimarto J, Brown MR, Buckbinder L, Carey DJ, Chasman DI, Chen X, Chen X, Chung J, Chutkow W, Cook JP, Delgado GE, Denaxas S, Doney AS, Dörr M, Dudley SC, Dunn ME, Engström G, Esko T, Felix SB, Finan C, Ford I, Ghanbari M, Ghasemi S, Giedraitis V, Giulianini F, Gottdiener JS, Gross S, Guðbjartsson DF, Gutmann R, Haggerty CM, van der Harst P, Hyde CL, Ingelsson E, Jukema JW, Kavousi M, Khaw KT, Kleber ME, Køber L, Koekemoer A, Langenberg C, Lind L, Lindgren CM, London B, Lotta LA, Lovering RC, Luan J, Magnusson P, Mahajan A, Margulies KB, März W, Melander O, Mordi IR, Morgan T, Morris AD, Morris AP, Morrison AC, Nagle MW, Nelson CP, Niessner A, Niiranen T, O’Donoghue ML, Owens AT, Palmer CNA, Parry HM, Perola M, Portilla-Fernandez E, Psaty BM, Rice KM, Ridker PM, Romaine SPR, Rotter JI, Salo P, Salomaa V, van Setten J, Shalaby AA, Smelser DT, Smith NL, Stender S, Stott DJ, Svensson P, Tammesoo ML, Taylor KD, Teder-Laving M, Teumer A, Thorgeirsson G, Thorsteinsdottir U, Torp-Pedersen C, Trompet S, Tyl B, Uitterlinden AG, Veluchamy A, Völker U, Voors AA, Wang X, Wareham NJ, Waterworth D, Weeke PE, Weiss R, Wiggins KL, Xing H, Yerges-Armstrong LM, Yu B, Zannad F, Zhao JH, Hemingway H, Samani NJ, McMurray JJV, Yang J, Visscher PM, Newton-Cheh C, Malarstig A, Holm H, Lubitz SA, Sattar N, Holmes MV, Cappola TP, Asselbergs FW, Hingorani AD, Kuchenbaecker K, Ellinor PT, Lang CC, Stefansson K, Smith JG, Vasan RS, Swerdlow DI, Lumbers RT. Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure. Nat Commun. 2020;11(1):163. Epub 2020/01/11. doi: 10.1038/s41467-019-13690-5. (PubMed ID Number: 31919418; PMCID: PMC6952380).

Staerk L, Preis SR, Lin H, Lubitz SA, Ellinor PT, Levy D, Benjamin EJ, Trinquart L. Protein Biomarkers and Risk of Atrial Fibrillation: The FHS. Circ Arrhythm Electrophysiol. 2020;13(2):e007607. Epub 2020/01/17. doi: 10.1161/circep.119.007607. (PubMed ID Number: 31941368; PMCID: PMC7031024).

Zhao YQ, Zhu R, Chen G, Zheng Y. Constructing dynamic treatment regimes with shared parameters for censored data. Stat Med. 2020;39(9):1250-63. Epub 2020/01/18. doi: 10.1002/sim.8473. (PubMed ID Number: 31951041).

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February

Agelink van Rentergem JA, de Vent NR, Schmand BA, Murre JMJ, Staaks JPC, Huizenga HM. The Factor Structure of Cognitive Functioning in Cognitively Healthy Participants: a Meta-Analysis and Meta-Analysis of Individual Participant Data. Neuropsychol Rev. 2020;30(1):51-96. Epub 2020/02/03. doi: 10.1007/s11065-019-09423-6. (PubMed ID Number: 32008158; PMCID: PMC7089912).

Arbeev KG, Verhulst S, Steenstrup T, Kark JD, Bagley O, Kooperberg C, Reiner AP, Hwang SJ, Levy D, Fitzpatrick AL, Christensen K, Yashin AI, Aviv A. Association of Leukocyte Telomere Length With Mortality Among Adult Participants in 3 Longitudinal Studies. JAMA Netw Open. 2020;3(2):e200023. Epub 2020/02/27. doi: 10.1001/jamanetworkopen.2020.0023. (PubMed ID Number: 32101305; PMCID: PMC7137690).

Feitosa MF, Lunetta KL, Wang L, Wojczynski MK, Kammerer CM, Perls T, Schupf N, Christensen K, Murabito JM, Province MA. Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies. Atherosclerosis. 2020;297:102-10. Epub 2020/02/29. doi: 10.1016/j.atherosclerosis.2020.02.005. (PubMed ID Number: 32109663).

Friedberg JS, Aytan N, Cherry JD, Xia W, Standring OJ, Alvarez VE, Nicks R, Svirsky S, Meng G, Jun G, Ryu H, Au R, Stein TD. Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E ε4 genotype. Sci Rep. 2020;10(1):2924. Epub 2020/02/23. doi: 10.1038/s41598-020-59869-5. (PubMed ID Number: 32076055; PMCID: PMC7031423).

Haslam DE, Peloso GM, Herman MA, Dupuis J, Lichtenstein AH, Smith CE, McKeown NM. Beverage Consumption and Longitudinal Changes in Lipoprotein Concentrations and Incident Dyslipidemia in US Adults: The Framingham Heart Study. J Am Heart Assoc. 2020;9(5):e014083. Epub 2020/02/27. doi: 10.1161/jaha.119.014083. (PubMed ID Number: 32098600).

Hruby A, Dennis C, Jacques PF. Dairy Intake in 2 American Adult Cohorts Associates with Novel and Known Targeted and Nontargeted Circulating Metabolites. J Nutr. 2020. Epub 2020/02/15. doi: 10.1093/jn/nxaa021. (PubMed ID Number: 32055836).

Ji H, Kim A, Ebinger JE, Niiranen TJ, Claggett BL, Merz CNB, Cheng S. Cardiometabolic Risk-Related Blood Pressure Trajectories Differ by Sex. Hypertension. 2020;75(4):e6-e9. Epub 2020/02/18. doi: 10.1161/hypertensionaha.119.14570. (PubMed ID Number: 32063062).

Kulminski AM, Shu L, Loika Y, He L, Nazarian A, Arbeev K, Ukraintseva S, Yashin A, Culminskaya I. Genetic and regulatory architecture of Alzheimer’s disease in the APOE region. Alzheimers Dement (Amst). 2020;12(1):e12008. Epub 2020/03/27. doi: 10.1002/dad2.12008. (PubMed ID Number: 32211503; PMCID: PMC7085286).

Nazarian A, Arbeev KG, Kulminski AM. The impact of disregarding family structure on genome-wide association analysis of complex diseases in cohorts with simple pedigrees. J Appl Genet. 2020;61(1):75-86. Epub 2019/11/23. doi: 10.1007/s13353-019-00526-7. (PubMed ID Number: 31755004; PMCID: PMC6980752).

Nwabuo CC, Vasan RS. Pathophysiology of Hypertensive Heart Disease: Beyond Left Ventricular Hypertrophy. Curr Hypertens Rep. 2020;22(2):11. Epub 2020/02/06. doi: 10.1007/s11906-020-1017-9. (PubMed ID Number: 32016791).

Posner DC, Lin H, Meigs JB, Kolaczyk ED, Dupuis J. Convex combination sequence kernel association test for rare-variant studies. Genet Epidemiol. 2020. Epub 2020/02/27. doi: 10.1002/gepi.22287. (PubMed ID Number: 32100372).

Shishtar E, Rogers GT, Blumberg JB, Au R, Jacques PF. Long-term dietary flavonoid intake and change in cognitive function in the Framingham Offspring cohort. Public Health Nutr. 2020:1-13. Epub 2020/02/25. doi: 10.1017/s136898001900394x. (PubMed ID Number: 32090722).

Wang Y, Beauchamp ME, Abrahamowicz M. Nonlinear and time-dependent effects of sparsely measured continuous time-varying covariates in time-to-event analysis. Biom J. 2020;62(2):492-515. Epub 2020/02/06. doi: 10.1002/bimj.201900042. (PubMed ID Number: 32022299).

Yang T, Wu C, Wei P, Pan W. Integrating DNA sequencing and transcriptomic data for association analyses of low-frequency variants and lipid traits. Hum Mol Genet. 2020;29(3):515-26. Epub 2020/01/11. doi: 10.1093/hmg/ddz314. (PubMed ID Number: 31919517; PMCID: PMC7015848).

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